Imaging findings of fahr’s syndrome may variable
Although Fahr’s syndrome (FS) was defined a long time ago, it is a rare disorder that may be overlooked in differential diagnosis. This often occurs especially when images specific to FS cannot be obtained. Patients with FS exhibit a wide variety of clinical symptoms. Neuropsychiatric disorders such as dystonia, parkinsonism, cognitive dysfunction, depression, schizoid disorders, obsessive-compulsive disorder and personality disorders are frequently seen (1). FS diagnosis is based on the evaluation of three main elements, including bilateral idiopathic non-atherosclerotic calcification of the basal ganglia, psychiatric symptoms, main movement disorders and neurological findings (2). In this paper, we report two FS cases whose standard magnetic resonance (MR) images were normal and who therefore were given a late diagnosis.
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- Chawla NA, Kakar GA, Fahr's disease as a presentation of progressive neurodegenerative disorder in an elderly: A case report. Current Medicine Research and Practice 4(3) 2014;123-125.
- Saleem S, Aslam HM, Anwar M, Anwar S, Saleem M, Saleem A, Rehmani MA. Fahr’s syndrome: literature review of current evidence. Orphanet Journal of Rare Diseases 2013, 8: 156.
- Sahin N,Solak A, Genc B, Kulu U. Fahr disease: use of susceptibility-weighted imaging for diagnostic dilemma with magnetic resonance imagingQuant Imaging Med Surg 2015;5(4):628-632.
- Ozer U, Gorgulu Y, Gungor FC, Gencturk M. Idiopathic Bilateral Basal Ganglia Calcification (Fahr’s Disease) Presenting with Psychotic Depression and Criminal Violence: A Case Report With Forensic Aspect. Journal Turkish Psychiatry. 2014;25(2):140-44.
- Lazar M, Ion DA, Streinu-Cercel A, Badarau AI. Fahr’s syndrome: Diagnosis issues in patients with unknown family history of disease. Rom J Morphol Embryo 2009; 50:425-8.
- BMJ Case Rep. Imaging in Fahr's disease: how CT and MRI differ? Govindarajan A. 2013 Nov 27;2013.